ANFD Discharge Isolators

ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators
ANFD Discharge Isolators

ANFD Discharge Isolators

Standard Group of Companies is a specialist at manufacturing process equipment such as Reactors and Agitated Nutsche Filter Dryers (ANFD's). As such Schematic design, manufacture and install bespoke, client specific Barrier Isolator systems to cGMP and cGAMP standards on such equipment where required.

Used for material from the agitate nutsche filter dryers.

For ANFD's we manufacture Rigid barrier isolator systems with either a negative or positive pressurised internal environment depending on the processed media.

Our negative (-ve) ANFD barrier isolators are essential where the process media is hazardous, dangerous or has an unacceptably high toxic level. This also provides a risk-free environment for the operator as potent vapours are taken to the systems filtered exhaust rather towards to operator. This design is the default standard for ANFD applications however if required, our positive (+ve) barrier isolators can be supplied where external contaminants can not be allowed to enter the processed batch substance.

Our Group ANFD designs feature a differential mixing agitator and paddle that moves vertically for a thorough mix performance. The filter drier agitator consists of a series of sharp curved blades that achieves mixing penetration into difficult cakes without undue product stress and can be supplied in a wide range of materials including Hastelloy. Click here to read further about the operational benefits of our turnkey supplied solution.

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Design Features

  • Integral ANFD Barrier Isolator - Permanently Fixed or Detatchable design
  • Rugged 316 Stainless Steel build with fully welded, large radius and polished corners
  • Push-push type safe changeable HEPA filters on inlet and outlet vents
  • cGAMP - PLC/HMI controlled - Digital pressure controller or Electrical controller to maintain a constant pressure
  • Integrated Clean In Place / washable to reach every corner of chamber
  • Integrated Weighing Scale, Nutsche Filter, Vacuum Tray Dryer, Continuous liner port and Drum loader
  • Laminar airflow
  • Oxygen monitoring / Nitrogen inertization
  • Complete Documentation – FDS, DQ, FAT, IQ, OQ, OMM, Leak test, Lux, Noise, Air change, Filter integrity, Glove test and OEL
  • Integration with RTP for safe and rapid transfer
  • Split Butterfly valve for safe transfer of material
  • Multiple or Single Chambers
  • Isolator raise/lower systems for operator comfort
  • Up to OEB-5 CategoryContainment.
  • Complete Inside area access.
  • Exhaust Double Filtration.
  • Chamber Auto Pressure ControlSystem.
  • Retractable Flexible spiralfor washing.
  • Isolator Access interlockswith Agitator running status.
  • Extendable Scrappers for ANFDmaterial unloading.
  • ANFD plug shall be handledthrough Isolator chamber.
  • ANFD Discharge plate intoIsolator chamber for easy material flow.

Technical Specification

  • ISO 14644-1: class ISO 5 (Class 100, Grade A)
  • Containment breach alarm
  • Low pressure and high pressure alarm
  • Filter choked alarm
  • Interlocked door system
  • HEPA Filters
  • Supplied to all OEL Categories OEL 1-5 (see Table)
  • Light Vacuum (100 Pa) system
  • Transfer System designs to suit application (optional)
  • Manual drum tippers (Automatic optional)

ISO-8 Environment inside.

MOC SS 316 L/ StanCoat-100/ETFE Coating/ Hastelloy.

Inside area access throughGlove Ports.

SS mirrors to view thecorners and edges.

Washable Pre Filterarrangement.

Full cladding on front side for aesthetic look of the Isolator.

Dried material sample through isolator.

OEL Hazards

Industry standard OEL hazard categories and descriptions are shown below. Schematic can supply Barrier Isolators to all OEL categories shown.

OEL 1 - Harmful and / or low pharmacological activity

OEL 2 - Harmful and / or moderate pharmacological activity

OEL 3 - Moderately toxic and / or high pharmacological activity

OEL 4 - Toxic and / or very high pharmacological activity

OEL 5 - Extremely toxic and / or extremely high pharmacological activity

Operational Benefit

  • Safe discharge of ANFD processed contents
  • Effective removal of CAKE
  • Clear visibility during operation and cleaning
  • Operator safety - fully interlocked air-locks, doors and visors
  • Uncontaminated process media
  • cGAMP - Alarms and safety measures in case of breach


Agitated Nutsche filter Dryers (ANFD) is a filtration technique used in applications such as;

  • Textiles and Dye
  • Paints, Varnish and surface coatings
  • Pharmaceutical production
  • Waste water treatment
  • API Industry.
  • Chemical Industry.
  • Especially used for handling High Potent chemicals.
  • Especially used for handling Hazardous materials.

Supply Options

  • Special design to handleLight Sensitive Products.
  • Inside Oxygen control System.
  • Inside Rh Controlled Systems.
  • Inside Temperature Controlsystems.
  • WIP and CIP Systems
  • Surface Finish in Matt orMirror.
  • Can be integrated to WeighingBalance.
  • RTP Integration.
  • Bin Integration
  • Poly Bottle integration.
  • Customized design based onspecific user requirements.
  • Isolator body welded to the ANFD or can be done with dismantlable type.

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